Syphilis antigen 
Syphilis is a sexually transmitted infection caused by Treponema pallidum. A total of 13,106 cases of primary and secondary syphilis were reported in the United States in 2011 and the rate of infection has increased in subgroups, particularly men who have sex with men. The disease is mainly diagnosed through clinical findings and serologic testing. However, no single serologic test of syphilis is sufficient. Hence, the serologic diagnosis of syphilis requires the detection of 2 types of antibodies (nontreponemal antibodies and treponemal antibodies). The paradigm in syphilis testing has recently shifted in many centers to screen with a treponemal antibody test, reflexing to a nontreponemal test if the treponemal antibody test is positive. This reverse of the traditional algorithm may not be widely recognized among clinicians.

Wuhan Aoke Botai Biotechnology Co., Ltd., formerly founded in 2002, is a high-tech company specializing in the R & D, production and sales of in vitro diagnostic raw materials (including antigens and antibodies). At the same time, it is a high-tech company that provides customized services for all kinds of monoclonal antibodies, multi-antibodies and recombinant proteins. After decades of development, Our company has passed 15013485 and 1509001 certification, and has won honors such as Optical Valley Gazelle, 3551 talents, provincial innovative small and medium-sized enterprises and provincial "specialized special new" small and medium-sized enterprises. After years of painstaking research and development, the company has created two major technology platforms that are widely praised in the industry, namely, mouse monoclonal antibody hybrid pain platform and recombinant protein expression platform. The mouse hybridoma platform is a leader in the industry, and we are the first company in China to use a pair of monoclonal antibodies to detect hepatitis B HBeAg. The recombinant protein platforms are E. coli expression platform, Pichia pastoris expression platform, insect cell-baculovirus expression system and mammalian cell expression platform. At the same time, the company also has 8000 square meters of animal feeding base, which can fully meet the supply needs of diagnostic reagent manufacturers.