• 100% NATURAL PRODUCT: No artificial colors or flavors
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• Third-party lab tested, pure Aurantii Fructus Immaturus

Plant morphology [base source] is the lime CitrusaurantiumL of rutaceae. Dried young fruit of its cultivated variety or sweet orange C. Sensisosbeck. Plant morphology Lime Citrusauran-tiumL. Small tree. Stems triangular, smooth, with long spines. Leaves degenerate into simple foliate, alternate, leathery; The petiole has narrow or inverted heart-shaped wings; Leaf blade oblong, apex short pure, acuminate, base broad cuneate or obtuse rounded, entire margin or indistinctly undulate serrate, both surfaces glabrous with oil spots, dorsal veins distinct. Flowers arranged in racemes, some solitary or clustered in axils; Calyx dish, 5-lobed; Petals 5, white, oblong; Stamens numerous, more than 20, filaments separated, long from stigma; Ovary superior, spherical, 12-locular, ovule numerous in each chamber, style cylindrical, stigma capitate. The fruit is round and slightly flat, orange-yellow when ripe, and the rind is rough.

     Hesperidin is a kind of flavonoid substance, with the structure of dihydroflavone oxyside, is weak acid. Pure products are white, needle-like crystals that form the main component of vitamin P. Hesperidin is hydrogenated into a natural sweetener, dihydrochardonone, which is 1,000 times sweeter than sucrose and can be used as a functional food.

AFI has been used to treat gastrointestinal diseases such as diarrhea, gasteremphraxis, and uterine prolapse. Flavonoids extracted from AFI have also been shown to inhibit liver inflammation, reduce oxidative stress damage, and protect the liver from fibrosis and lipotoxicity. Other studies have found that AFI can increase the cytolytic activity of primary natural killer cells and promote the gastric empting process in rats.
 

Aurantii Fructus Immaturus (AFI) is a traditional Chinese medicine (TCM) herb that's been used to treat many diseases, including obesity, diabetes, cardiovascular disease, and gastrointestinal issues. AFI is derived from the bitter orange, Citrus aurantium, and contains bioactive ingredients like flavonoids, alkaloids, volatile oils, and coumarins. These ingredients have many potential health benefits, including: 
Anticancer 
Anti-inflammatory 
Antioxidant 
Antifungal 
Anti-anxiety 
Gastric mucosa protective 
Intestinal motility regulatory 
Nerve protective 
One study found that AFI can also enhance the activity of natural killer (NK) cells, which are important for the immune system. AFI treatment increased the expression of NK cell-activating receptors, such as NKp30 and NKp46, and cytolytic granules. This allowed AFI-treated NK cells to kill target cells more effectively than untreated NK cells. 

 

* The statements in this section have not been evaluated by the FDA or EFSA.

References

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    4.Li X, Dai E, Li M, Kong R, Yuan J, Li T, Wang S, Zhang Y, Kong H, Zhao Y.Front Mol Biosci. 2024 Jan 8;10:1334083. doi: 10.3389/fmolb.2023.1334083. eCollection 2023.PMID: 38259687
    5.Wang LF, Liu XL, Li HT, Chen QY, Wang Y, Zou B, Yang M, Zhang XF, Wang F.Zhongguo Zhong Yao Za Zhi. 2020 Apr;45(8):1909-1917. doi: 10.19540/j.cnki.cjcmm.20200207.302.PMID: 32489077